all laboratories should now be using a creatinine method that has been standardized or traceable to isotope dilution mass spectrometry (IDMS). The way creatinine levels are calibrated affects the GFR estimating equation slightly.
to properly estimate GFR, the serum creatinine must be measured accurately. When a laboratory calibrates their method to the single standardized serum creatinine using reference materials traceable to the primary reference material at the National Institute of Standards, we say that value is traceable to IDMS because the test is based on isotope dilution mass spectrometry (IDMS).
with the exception of the Cockcroft-Gault formula, all other calculators in this Smartphone application are designed for use with standardized creatinine values that are traceable to IDMS. Also, only standardized cystatin C values are used.
your laboratory can confirm whether or not it uses standardized creatinine values that are traceable to IDMS. It can also confirm whether it uses cystatin C values that are standardized.
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