The home page

2013/06/28

Stem Cell and cancer of the kidney




Kidney cancer, or cancer of the kidney, is any type of cancer that has arisen from the kidney. Kidney cancer does not usually include a cancer that arose outside the kidney and metastasized to include metastatic cancer of the kidney. 

The most common types of kidney cancer include renal cell carcinoma and urothelial cell carcinoma of the renal pelvis. Renal cell carcinoma accounts for approximately 90% of all kidney cancers. Urothelial cell carcinoma is a type of cancer that occurs in the urinary system, specifically the kidney, urinary bladder, ureter, urethra and urachus. 

The following are also types of kidney cancers:
Squamous cell carcinoma
Juxtaglomerular cell tumor (reninoma)
Angiomyolipoma
Renal oncocytoma
Bellini duct carcinoma
Clear-cell sarcoma of the kidney
Mesoblastic nephroma
Wilms' tumor (usually diagnosed in children under 5)
Mixed epithelial stromal tumor
Adults aged between 50 and 80 years are more likely to develop kidney cancer compared to other people. This type of cancer affects men more than women. 

The incidence of kidney cancer in the developed world has been steadily increasing over the last three decades. Some experts believe there is a close link between this increase and a parallel rise in rates of adult obesity. 

Chemotherapy is designed to treat cancer cells that may have spread in this fashion. Sadly, even with chemotherapy cells may survive and begin to grow at a later date. Cancer that returns. Cancer survivors have a risk of cancer recurrence before  cancer killer cells treatment.

Stem cell therapy for kidney transplant help




One of the biggest remaining hurdles in organ transplantation remains the need for powerful anti-rejection and immune-suppressing medications after the transplant.

Basically, the way we prevent kidney rejections is by putting you on very powerful anti-rejection drugs and immunosuppressive agents to prevent your cells from attacking the foreign organ. But, the current standard has some problems, like an increased risk of infections and the possibility of creating a cancer.

The body’s immune system sends out surveillance cells to protect the body against foreign invaders, such as a bacteria, virus or, in this case, a new organ. The current method of preventing these cells from attacking the new organ is essentially to destroy the surveillance cells. But mesenchymal cells can naturally suppress those surveillance cells so they don’t attack.

If you infuse mesenchymal stem cells at the time of the transplant, you could replace the use of powerful anti-rejection drugs, and maybe replace immunosuppressants altogether.